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Roles of sphingosine-1-phosphate signaling in cancer

The potent pleiotropic lipid mediator sphingosine-1-phosphate (S1P) participates in numerous cellular processes, including angiogenesis and cell survival, proliferation, and migration. It is formed by one of two sphingosine kinases (SphKs), SphK1 and SphK2. These enzymes largely exert their various...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Yuan, Yonghui, Lin, Wenda, Zhong, Hongshan, Xu, Ke, Qi, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857321/
https://www.ncbi.nlm.nih.gov/pubmed/31807117
http://dx.doi.org/10.1186/s12935-019-1014-8