Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism

Continued CRISPR/Cas9-mediated editing activity that allows differential and asynchronous modification of alleles in successive cell generations expands allelic complexity. To understand the earliest events during CRISPR/Cas9 editing and the allelic selection among the progeny of subsequent cell div...

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Detalles Bibliográficos
Autores principales: Jeon, Jeehyun, Park, Jung Sun, Min, Byungkuk, Chung, Sun-Ku, Kim, Min Kyu, Kang, Yong-Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857330/
https://www.ncbi.nlm.nih.gov/pubmed/31781562
http://dx.doi.org/10.3389/fcell.2019.00273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857330/
https://www.ncbi.nlm.nih.gov/pubmed/31781562
http://dx.doi.org/10.3389/fcell.2019.00273

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