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Application of CRISPR genetic screens to investigate neurological diseases

The adoption of CRISPR-Cas9 technology for functional genetic screens has been a transformative advance. Due to its modular nature, this technology can be customized to address a myriad of questions. To date, pooled, genome-scale studies have uncovered genes responsible for survival, proliferation,...

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Detalles Bibliográficos
Autores principales: So, Raphaella W. L., Chung, Sai Wai, Lau, Heather H. C., Watts, Jeremy J., Gaudette, Erin, Al-Azzawi, Zaid A. M., Bishay, Jossana, Lin, Lilian Tsai-Wei, Joung, Julia, Wang, Xinzhu, Schmitt-Ulms, Gerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857349/
https://www.ncbi.nlm.nih.gov/pubmed/31727120
http://dx.doi.org/10.1186/s13024-019-0343-3