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Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour

The cannabinoid-1 receptor (CB(1)) plays a critical role in a number of biological processes including nutrient intake, addiction and anxiety-related behaviour. Numerous studies have shown that expression of the gene encoding CB1 (CNR1) is highly dynamic with changes in the tissue specific expressio...

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Detalles Bibliográficos
Autores principales: Hay, Elizabeth A., McEwan, Andrew, Wilson, Dana, Barrett, Perry, D’Agostino, Giuseppe, Pertwee, Roger G., MacKenzie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857436/
https://www.ncbi.nlm.nih.gov/pubmed/31445429
http://dx.doi.org/10.1016/j.psyneuen.2019.104407