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Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour
The cannabinoid-1 receptor (CB(1)) plays a critical role in a number of biological processes including nutrient intake, addiction and anxiety-related behaviour. Numerous studies have shown that expression of the gene encoding CB1 (CNR1) is highly dynamic with changes in the tissue specific expressio...
Autores principales: | Hay, Elizabeth A., McEwan, Andrew, Wilson, Dana, Barrett, Perry, D’Agostino, Giuseppe, Pertwee, Roger G., MacKenzie, Alasdair |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857436/ https://www.ncbi.nlm.nih.gov/pubmed/31445429 http://dx.doi.org/10.1016/j.psyneuen.2019.104407 |
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