Differential Effects of the Mitochondria-Active Tetrapeptide SS-31 (D-Arg-dimethylTyr-Lys-Phe-NH(2)) and Its Peptidase-Targeted Prodrugs in Experimental Acute Kidney Injury

The mitochondria-active tetrapeptide SS-31 can control oxidative tissue damage in kidney diseases. To investigate other potential beneficial nephroprotective effects of SS-31, in vivo murine models of acute tubular injury and glomerular damage were developed. Reduction of acute kidney injury was dem...

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Detalles Bibliográficos
Autores principales: Wyss, Jean-Christophe, Kumar, Rajesh, Mikulic, Josip, Schneider, Manfred, Mary, Jean-Luc, Aebi, Johannes D., Juillerat-Jeanneret, Lucienne, Golshayan, Dela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857474/
https://www.ncbi.nlm.nih.gov/pubmed/31780923
http://dx.doi.org/10.3389/fphar.2019.01209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857474/
https://www.ncbi.nlm.nih.gov/pubmed/31780923
http://dx.doi.org/10.3389/fphar.2019.01209

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