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Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study)

BACKGROUND: To evaluate clinical outcomes after either immediate or deferred initiation of antiretroviral therapy in HIV-1-infected patients, presenting late with pneumocystis pneumonia (PCP) or toxoplasma encephalitis (TE). METHODS: Phase IV, multicenter, prospective, randomized open-label clinical...

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Detalles Bibliográficos
Autores principales: Schäfer, Guido, Hoffmann, Christian, Arasteh, Keikawus, Schürmann, Dirk, Stephan, Christoph, Jensen, Björn, Stoll, Matthias, Bogner, Johannes R., Faetkenheuer, Gerd, Rockstroh, Jürgen, Klinker, Hartwig, Härter, Georg, Stöhr, Albrecht, Degen, Olaf, Freiwald, Eric, Hüfner, Anja, Jordan, Sabine, Schulze zur Wiesch, Julian, Addo, Marylyn, Lohse, Ansgar W., van Lunzen, Jan, Schmiedel, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857475/
https://www.ncbi.nlm.nih.gov/pubmed/31729999
http://dx.doi.org/10.1186/s12981-019-0250-2