Cargando…

Phosphorylation of nephrin induces phase separated domains that move through actomyosin contraction

The plasma membrane of eukaryotic cells is organized into lipid and protein microdomains, whose assembly mechanisms and functions are incompletely understood. We demonstrate that proteins in the nephrin/Nck/N-WASP actin-regulatory pathway cluster into micron-scale domains at the basal plasma membran...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Soyeon, Kalappurakkal, Joseph M., Mayor, Satyajit, Rosen, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857567/
https://www.ncbi.nlm.nih.gov/pubmed/31599693
http://dx.doi.org/10.1091/mbc.E18-12-0823