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Phosphorylation of nephrin induces phase separated domains that move through actomyosin contraction
The plasma membrane of eukaryotic cells is organized into lipid and protein microdomains, whose assembly mechanisms and functions are incompletely understood. We demonstrate that proteins in the nephrin/Nck/N-WASP actin-regulatory pathway cluster into micron-scale domains at the basal plasma membran...
Autores principales: | Kim, Soyeon, Kalappurakkal, Joseph M., Mayor, Satyajit, Rosen, Michael K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857567/ https://www.ncbi.nlm.nih.gov/pubmed/31599693 http://dx.doi.org/10.1091/mbc.E18-12-0823 |
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