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Mitochondrial lipid droplet formation as a detoxification mechanism to sequester and degrade excessive urothelial membranes
The apical surface of the terminally differentiated mammalian urothelial umbrella cell is mechanically stable and highly impermeable, in part due to its coverage by urothelial plaques consisting of 2D crystals of uroplakin particles. The mechanism for regulating the uroplakin/plaque level is unclear...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857570/ https://www.ncbi.nlm.nih.gov/pubmed/31577526 http://dx.doi.org/10.1091/mbc.E19-05-0284 |