Mitochondrial lipid droplet formation as a detoxification mechanism to sequester and degrade excessive urothelial membranes

The apical surface of the terminally differentiated mammalian urothelial umbrella cell is mechanically stable and highly impermeable, in part due to its coverage by urothelial plaques consisting of 2D crystals of uroplakin particles. The mechanism for regulating the uroplakin/plaque level is unclear...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Yi, Tham, Daniel K. L., Liang, Feng-Xia, Chang, Jennifer, Wei, Yuan, Sudhir, Putty-Reddy, Sall, Joseph, Ren, Sarah J., Chicote, Javier U., Arnold, Lora L., Hu, Chih-Chi Andrew, Romih, Rok, Andrade, Leonardo R., Rindler, Michael J., Cohen, Samuel M., DeSalle, Rob, Garcia-España, Antonio, Ding, Mingxiao, Wu, Xue-Ru, Sun, Tung-Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857570/
https://www.ncbi.nlm.nih.gov/pubmed/31577526
http://dx.doi.org/10.1091/mbc.E19-05-0284

Ejemplares similares

Ejemplares similares