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A Supramolecular Interaction of a Ruthenium Complex With Calf-Thymus DNA: A Ligand Binding Approach by NMR Spectroscopy

Lawsone itself exhibits interesting biological activities, and its complexation with a metal center can improve the potency. In this context a cytotoxic Ru-complex, [Ru(law)(dppb)(bipy)] (law = lawsone, dppb = 1,4-bis(diphenylphosphino)butane and bipy = 2,2′-bipyridine), named as CBLAU, was prepared...

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Detalles Bibliográficos
Autores principales: Kock, Flávio Vinícius Crizóstomo, Costa, Analu Rocha, de Oliveira, Katia Mara, Batista, Alzir Azevedo, Ferreira, Antônio Gilberto, Venâncio, Tiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857657/
https://www.ncbi.nlm.nih.gov/pubmed/31781544
http://dx.doi.org/10.3389/fchem.2019.00762