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Co-cultivation With 5-Azacytidine Induced New Metabolites From the Zoanthid-Derived Fungus Cochliobolus lunatus

The zoanthid-derived fungus Cochliobolus lunatus (TA26-46) has been proven to be a source of bioactive 14-membered resorcylic acid lactones (RALs). In the present study, chemical epigenetic manipulation was applied to this fungal strain with a DNA methyltransferase inhibitor resulting in the signifi...

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Detalles Bibliográficos
Autores principales: Wu, Jing-Shuai, Shi, Xiao-Hui, Zhang, Ya-Hui, Yu, Jia-Yin, Fu, Xiu-Mei, Li, Xin, Chen, Kai-Xian, Guo, Yue-Wei, Shao, Chang-Lun, Wang, Chang-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857680/
https://www.ncbi.nlm.nih.gov/pubmed/31781545
http://dx.doi.org/10.3389/fchem.2019.00763