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Training rhesus macaques to take daily oral antiretroviral therapy for preclinical evaluation of HIV prevention and treatment strategies

BACKGROUND: Macaque models of simian or simian/human immunodeficiency virus (SIV or SHIV) infection are critical for the evaluation of antiretroviral (ARV)-based HIV treatment and prevention strategies. However, modelling human oral ARV administration is logistically challenging and fraught by limit...

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Detalles Bibliográficos
Autores principales: Daly, Michele B., Clayton, April M., Ruone, Susan, Mitchell, James, Dinh, Chuong, Holder, Angela, Jolly, Julian, García-Lerma, J. Gerardo, Weed, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857902/
https://www.ncbi.nlm.nih.gov/pubmed/31730629
http://dx.doi.org/10.1371/journal.pone.0225146