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Training rhesus macaques to take daily oral antiretroviral therapy for preclinical evaluation of HIV prevention and treatment strategies
BACKGROUND: Macaque models of simian or simian/human immunodeficiency virus (SIV or SHIV) infection are critical for the evaluation of antiretroviral (ARV)-based HIV treatment and prevention strategies. However, modelling human oral ARV administration is logistically challenging and fraught by limit...
Autores principales: | Daly, Michele B., Clayton, April M., Ruone, Susan, Mitchell, James, Dinh, Chuong, Holder, Angela, Jolly, Julian, García-Lerma, J. Gerardo, Weed, James L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857902/ https://www.ncbi.nlm.nih.gov/pubmed/31730629 http://dx.doi.org/10.1371/journal.pone.0225146 |
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