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Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish

Their optical clarity as larvae and embryos, small size, and high fecundity make zebrafish ideal for whole animal high throughput screening. A high-throughput drug discovery platform (HTP) has been built to perform fully automated screens of compound libraries with zebrafish embryos. A Tg(kdrl:EGFP)...

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Detalles Bibliográficos
Autores principales: Mauro, Antonio, Ng, Robin, Li, Jamie Yuanjun, Guan, Rui, Wang, Youdong, Singh, Krishna Kumar, Wen, Xiao-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857904/
https://www.ncbi.nlm.nih.gov/pubmed/31730619
http://dx.doi.org/10.1371/journal.pone.0221796