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Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish
Their optical clarity as larvae and embryos, small size, and high fecundity make zebrafish ideal for whole animal high throughput screening. A high-throughput drug discovery platform (HTP) has been built to perform fully automated screens of compound libraries with zebrafish embryos. A Tg(kdrl:EGFP)...
Autores principales: | Mauro, Antonio, Ng, Robin, Li, Jamie Yuanjun, Guan, Rui, Wang, Youdong, Singh, Krishna Kumar, Wen, Xiao-Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857904/ https://www.ncbi.nlm.nih.gov/pubmed/31730619 http://dx.doi.org/10.1371/journal.pone.0221796 |
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