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A robust multi-objective optimization framework to capture both cellular and intercellular properties in cardiac cellular model tuning: Analyzing different regions of membrane resistance profile in parameter fitting

Mathematical models of cardiac cells have been established to broaden understanding of cardiac function. In the process of developing electrophysiological models for cardiac myocytes, precise parameter tuning is a crucial step. The membrane resistance (R(m)) is an essential feature obtained from car...

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Detalles Bibliográficos
Autores principales: Pouranbarani, Elnaz, Weber dos Santos, Rodrigo, Nygren, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857942/
https://www.ncbi.nlm.nih.gov/pubmed/31730631
http://dx.doi.org/10.1371/journal.pone.0225245