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Binding Immunoglobulin Protein (BIP) Inhibits TNF‐α–Induced Osteoclast Differentiation and Systemic Bone Loss in an Erosive Arthritis Model
OBJECTIVE: The association between inflammation and dysregulated bone remodeling is apparent in rheumatoid arthritis and is recapitulated in the human tumor necrosis factor transgenic (hTNFtg) mouse model. We investigated whether extracellular binding immunoglobulin protein (BiP) would protect the h...
Autores principales: | Zaiss, Mario M., Hall, Christopher, McGowan, Neil W. A., Babb, Rebecca, Devlia, Vikesh, Lucas, Sébastien, Meghji, Sajeda, Henderson, Brian, Bozec, Aline, Schett, Georg, David, Jean‐Pierre, Panayi, Gabriel S., Grigoriadis, Agamemnon E., Corrigall, Valerie M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857990/ https://www.ncbi.nlm.nih.gov/pubmed/31777818 http://dx.doi.org/10.1002/acr2.11060 |
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