The CoDiNOS trial protocol: an international randomised controlled trial of intravenous sildenafil versus inhaled nitric oxide for the treatment of pulmonary hypertension in neonates with congenital diaphragmatic hernia

INTRODUCTION: Congenital diaphragmatic hernia (CDH) is a developmental defect of the diaphragm that impairs normal lung development, causing pulmonary hypertension (PH). PH in CDH newborns is the main determinant for morbidity and mortality. Different therapies are still mainly based on ‘trial and e...

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Detalles Bibliográficos
Autores principales: Cochius-den Otter, Suzan, Schaible, Thomas, Greenough, Anne, van Heijst, Arno, Patel, Neil, Allegaert, Karel, van Rosmalen, Joost, Tibboel, Dick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Paediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858099/
https://www.ncbi.nlm.nih.gov/pubmed/31694851
http://dx.doi.org/10.1136/bmjopen-2019-032122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858099/
https://www.ncbi.nlm.nih.gov/pubmed/31694851
http://dx.doi.org/10.1136/bmjopen-2019-032122

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