PD-1(+) melanocortin receptor dependent-Treg cells prevent autoimmune disease

Experimental autoimmune uveoretinitis (EAU) is a mouse model of human autoimmune uveitis marked by ocular autoantigen-specific regulatory immunity in the spleen. The melanocortin 5 receptor (MC5r) and adenosine 2 A receptor (A2Ar) are required for induction of post-EAU regulatory T cells (Tregs) whi...

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Detalles Bibliográficos
Autores principales: Muhammad, Fauziyya, Wang, Dawei, Montieth, Alyssa, Lee, Stacey, Preble, Janine, Foster, C. Stephen, Larson, Theresa A., Ding, Kai, Dvorak, Justin D., Lee, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858311/
https://www.ncbi.nlm.nih.gov/pubmed/31729418
http://dx.doi.org/10.1038/s41598-019-53297-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858311/
https://www.ncbi.nlm.nih.gov/pubmed/31729418
http://dx.doi.org/10.1038/s41598-019-53297-w

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