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Multiple conformations facilitate PilT function in the type IV pilus

Type IV pilus-like systems are protein complexes that polymerize pilin fibres. They are critical for virulence in many bacterial pathogens. Pilin polymerization and depolymerization are powered by motor ATPases of the PilT/VirB11-like family. This family is thought to operate with C(2) symmetry; how...

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Detalles Bibliográficos
Autores principales: McCallum, Matthew, Benlekbir, Samir, Nguyen, Sheryl, Tammam, Stephanie, Rubinstein, John L., Burrows, Lori L., Howell, P. Lynne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858323/
https://www.ncbi.nlm.nih.gov/pubmed/31729381
http://dx.doi.org/10.1038/s41467-019-13070-z