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Thermosensitive PBP2a requires extracellular folding factors PrsA and HtrA1 for Staphylococcus aureus MRSA β-lactam resistance
Staphylococcus aureus is a major human pathogen and represents a clinical challenge because of widespread antibiotic resistance. Methicillin resistant Staphylococcus aureus (MRSA) is particularly problematic and originates by the horizontal acquisition of mecA encoding PBP2a, an extracellular membra...
Autores principales: | Roch, Mélanie, Lelong, Emmanuelle, Panasenko, Olesya O., Sierra, Roberto, Renzoni, Adriana, Kelley, William L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858329/ https://www.ncbi.nlm.nih.gov/pubmed/31754647 http://dx.doi.org/10.1038/s42003-019-0667-0 |
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