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Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference

Alpha-synuclein (α-syn) is an abundant neuroprotein elevated in cocaine addicts, linked to drug craving, and recruited to axon terminals undergoing glutamatergic plasticity - a proposed mechanism for substance abuse. However, little is known about normal α-syn function or how it contributes to subst...

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Detalles Bibliográficos
Autores principales: Trubetckaia, Olga, Lane, Ariana E., Qian, Liping, Zhou, Ping, Lane, Diane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858354/
https://www.ncbi.nlm.nih.gov/pubmed/31754648
http://dx.doi.org/10.1038/s42003-019-0651-8