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Targeted Multiple Reaction Monitoring Analysis of CSF Identifies UCHL1 and GPNMB as Candidate Biomarkers for ALS

The neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) share some common molecular deficits including disruption of protein homeostasis leading to disease-specific protein aggregation. While insoluble protein aggregates are the defining pathological confirmat...

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Detalles Bibliográficos
Autores principales: Zhu, Shaochun, Wuolikainen, Anna, Wu, Junfang, Öhman, Anders, Wingsle, Gunnar, Moritz, Thomas, Andersen, Peter M., Forsgren, Lars, Trupp, Miles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858390/
https://www.ncbi.nlm.nih.gov/pubmed/31721001
http://dx.doi.org/10.1007/s12031-019-01411-y