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Targeted Multiple Reaction Monitoring Analysis of CSF Identifies UCHL1 and GPNMB as Candidate Biomarkers for ALS
The neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) share some common molecular deficits including disruption of protein homeostasis leading to disease-specific protein aggregation. While insoluble protein aggregates are the defining pathological confirmat...
Autores principales: | Zhu, Shaochun, Wuolikainen, Anna, Wu, Junfang, Öhman, Anders, Wingsle, Gunnar, Moritz, Thomas, Andersen, Peter M., Forsgren, Lars, Trupp, Miles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858390/ https://www.ncbi.nlm.nih.gov/pubmed/31721001 http://dx.doi.org/10.1007/s12031-019-01411-y |
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