Computational redesign of the Escherichia coli ribose-binding protein ligand binding pocket for 1,3-cyclohexanediol and cyclohexanol

Bacterial periplasmic-binding proteins have been acclaimed as general biosensing platform, but their range of natural ligands is too limited for optimal development of chemical compound detection. Computational redesign of the ligand-binding pocket of periplasmic-binding proteins may yield variants...

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Detalles Bibliográficos
Autores principales: Tavares, Diogo, Reimer, Artur, Roy, Shantanu, Joublin, Aurélie, Sentchilo, Vladimir, van der Meer, Jan Roelof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858440/
https://www.ncbi.nlm.nih.gov/pubmed/31729460
http://dx.doi.org/10.1038/s41598-019-53507-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858440/
https://www.ncbi.nlm.nih.gov/pubmed/31729460
http://dx.doi.org/10.1038/s41598-019-53507-5

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