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Modular actin nano-architecture enables podosome protrusion and mechanosensing

Basement membrane transmigration during embryonal development, tissue homeostasis and tumor invasion relies on invadosomes, a collective term for invadopodia and podosomes. An adequate structural framework for this process is still missing. Here, we reveal the modular actin nano-architecture that en...

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Detalles Bibliográficos
Autores principales: van den Dries, Koen, Nahidiazar, Leila, Slotman, Johan A., Meddens, Marjolein B. M., Pandzic, Elvis, Joosten, Ben, Ansems, Marleen, Schouwstra, Joost, Meijer, Anke, Steen, Raymond, Wijers, Mietske, Fransen, Jack, Houtsmuller, Adriaan B., Wiseman, Paul W., Jalink, Kees, Cambi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858452/
https://www.ncbi.nlm.nih.gov/pubmed/31729386
http://dx.doi.org/10.1038/s41467-019-13123-3