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Molecular mechanism of cotranslational membrane protein recognition and targeting by SecA

Cotranslational protein targeting is a conserved process for membrane protein biogenesis. In Escherichia coli, the essential ATPase SecA was found to cotranslationally target a subset of nascent membrane proteins to the SecYEG translocase at the plasma membrane. The molecular mechanism of this pathw...

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Detalles Bibliográficos
Autores principales: Wang, Shuai, Jomaa, Ahmad, Jaskolowski, Mateusz, Yang, Chien-I, Ban, Nenad, Shan, Shu-ou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858539/
https://www.ncbi.nlm.nih.gov/pubmed/31570874
http://dx.doi.org/10.1038/s41594-019-0297-8