An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

We generated parietal cortex RNA-seq data from individuals with and without Alzheimer disease (AD; n(control) = 13; n(AD) = 83) from the Knight-ADRC. Using this and an independent (MSBB) AD RNA-seq dataset, we quantified cortical circular RNA (circRNA) expression in the context of AD. We identified...

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Detalles Bibliográficos
Autores principales: Dube, Umber, Del-Aguila, Jorge L, Li, Zeran, Budde, John P, Jiang, Shan, Hsu, Simon, Ibanez, Laura, Fernandez, Maria Victoria, Farias, Fabiana, Norton, Joanne, Gentsch, Jen, Wang, Fengxian, Salloway, Stephen, Masters, Colin L, Lee, Jae-Hong, Graff-Radford, Neill R, Chhatwal, Jasmeer P, Bateman, Randall J, Morris, John C, Karch, Celeste M, Harari, Oscar, Cruchaga, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858549/
https://www.ncbi.nlm.nih.gov/pubmed/31591557
http://dx.doi.org/10.1038/s41593-019-0501-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858549/
https://www.ncbi.nlm.nih.gov/pubmed/31591557
http://dx.doi.org/10.1038/s41593-019-0501-5

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