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An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations
We generated parietal cortex RNA-seq data from individuals with and without Alzheimer disease (AD; n(control) = 13; n(AD) = 83) from the Knight-ADRC. Using this and an independent (MSBB) AD RNA-seq dataset, we quantified cortical circular RNA (circRNA) expression in the context of AD. We identified...
Autores principales: | Dube, Umber, Del-Aguila, Jorge L, Li, Zeran, Budde, John P, Jiang, Shan, Hsu, Simon, Ibanez, Laura, Fernandez, Maria Victoria, Farias, Fabiana, Norton, Joanne, Gentsch, Jen, Wang, Fengxian, Salloway, Stephen, Masters, Colin L, Lee, Jae-Hong, Graff-Radford, Neill R, Chhatwal, Jasmeer P, Bateman, Randall J, Morris, John C, Karch, Celeste M, Harari, Oscar, Cruchaga, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858549/ https://www.ncbi.nlm.nih.gov/pubmed/31591557 http://dx.doi.org/10.1038/s41593-019-0501-5 |
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