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Population imaging of neural activity in awake behaving mice

A longstanding goal in neuroscience has been to image membrane voltage across a population of individual neurons in an awake, behaving mammal. Here, we report a genetically encoded fluorescent voltage indicator, SomArchon, which exhibits millisecond response times and compatibility with optogenetic...

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Detalles Bibliográficos
Autores principales: Piatkevich, Kiryl D., Bensussen, Seth, Tseng, Hua-an, Shroff, Sanaya N., Lopez-Huerta, Violeta Gisselle, Park, Demian, Jung, Erica E., Shemesh, Or A., Straub, Christoph, Gritton, Howard J., Romano, Michael F., Costa, Emma, Sabatini, Bernardo L., Fu, Zhanyan, Boyden, Edward S., Han, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858559/
https://www.ncbi.nlm.nih.gov/pubmed/31597963
http://dx.doi.org/10.1038/s41586-019-1641-1