RBPJ-dependent Notch signaling initiates the T cell program in a subset of thymus-seeding progenitors

T cell specification and commitment requires Notch signaling. Although the requirement for Notch signaling during intrathymic T cell development is known, it is still unclear whether the onset of T cell priming can occur in a pre-thymic niche and whether RBPJ-dependent Notch signaling has a role dur...

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Detalles Bibliográficos
Autores principales: Chen, Edward L. Y., Thompson, Patrycja K., Zúñiga-Pflücker, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858571/
https://www.ncbi.nlm.nih.gov/pubmed/31636466
http://dx.doi.org/10.1038/s41590-019-0518-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858571/
https://www.ncbi.nlm.nih.gov/pubmed/31636466
http://dx.doi.org/10.1038/s41590-019-0518-7

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