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Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2)

BACKGROUND: Neurofibromatosis 1 and 2, although involving two different tumour suppressor genes (neurofibromin and merlin, respectively), are both cancer predisposition syndromes that disproportionately affect cells of neural crest origin. New therapeutic approaches for both NF1 and NF2 are badly ne...

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Detalles Bibliográficos
Autores principales: Shen, Yu-chi, Arellano-Garcia, Caroline, Menjivar, Rosa E., Jewett, Ethan M., Dohle, Wolfgang, Karchugina, Sofiia, Chernoff, Jonathan, Potter, Barry V. L., Barald, Kate F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858664/
https://www.ncbi.nlm.nih.gov/pubmed/31730023
http://dx.doi.org/10.1186/s40360-019-0369-8