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Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). While the clinical presentation of LRRK2 mutation carriers is similar to that of idiopathic PD (iPD) patients, the neuropathology of LRRK2 PD is less clearly defined. Lewy bodies (LBs) c...

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Detalles Bibliográficos
Autores principales: Henderson, Michael X., Sengupta, Medha, Trojanowski, John Q., Lee, Virginia M. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858668/
https://www.ncbi.nlm.nih.gov/pubmed/31733655
http://dx.doi.org/10.1186/s40478-019-0836-x