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Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability to promote prostate cancer cell migration and invasion

BACKGROUND: Progression of prostate cancer from benign local tumors to metastatic carcinomas is a multistep process. Here we have investigated the signaling pathways that support migration and invasion of prostate cancer cells, focusing on the role of the NFATC1 transcription factor and its post-tra...

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Detalles Bibliográficos
Autores principales: Eerola, Sini K., Santio, Niina M., Rinne, Sanni, Kouvonen, Petri, Corthals, Garry L., Scaravilli, Mauro, Scala, Giovanni, Serra, Angela, Greco, Dario, Ruusuvuori, Pekka, Latonen, Leena, Rainio, Eeva-Marja, Visakorpi, Tapio, Koskinen, Päivi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858710/
https://www.ncbi.nlm.nih.gov/pubmed/31730483
http://dx.doi.org/10.1186/s12964-019-0463-y