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Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability to promote prostate cancer cell migration and invasion
BACKGROUND: Progression of prostate cancer from benign local tumors to metastatic carcinomas is a multistep process. Here we have investigated the signaling pathways that support migration and invasion of prostate cancer cells, focusing on the role of the NFATC1 transcription factor and its post-tra...
Autores principales: | Eerola, Sini K., Santio, Niina M., Rinne, Sanni, Kouvonen, Petri, Corthals, Garry L., Scaravilli, Mauro, Scala, Giovanni, Serra, Angela, Greco, Dario, Ruusuvuori, Pekka, Latonen, Leena, Rainio, Eeva-Marja, Visakorpi, Tapio, Koskinen, Päivi J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858710/ https://www.ncbi.nlm.nih.gov/pubmed/31730483 http://dx.doi.org/10.1186/s12964-019-0463-y |
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