USP7 is a novel Deubiquitinase sustaining PLK1 protein stability and regulating chromosome alignment in mitosis

BACKGROUND: The deubiquitinase USP7 has been identified as an oncogene with key roles in tumorigenesis and therapeutic resistance for a series of cancer types. Recently small molecular inhibitors have been developed to target USP7. However, the anticancer mechanism of USP7 inhibitors is still elusiv...

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Detalles Bibliográficos
Autores principales: Peng, Yuchong, Liu, Youhong, Gao, Yingxue, Yuan, Bowen, Qi, Xuli, Fu, Yuxin, Zhu, Qianling, Cao, Tuoyu, Zhang, Songwei, Yin, Linglong, Li, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858727/
https://www.ncbi.nlm.nih.gov/pubmed/31730000
http://dx.doi.org/10.1186/s13046-019-1457-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858727/
https://www.ncbi.nlm.nih.gov/pubmed/31730000
http://dx.doi.org/10.1186/s13046-019-1457-8

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