Supplementation of vitamin C promotes early germ cell specification from human embryonic stem cells

BACKGROUND: As the precursors of sperm and eggs, human primordial germ cells (hPGCs) emerge as early as weeks 2 to 3 of post-implantation development. Recently, robust hPGC induction models have been established in vitro with different protocols, but global 5mC/5hmC epigenetic reprogramming is not i...

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Detalles Bibliográficos
Autores principales: Li, Zili, Fang, Fang, Zhao, Qian, Li, Honggang, Xiong, Chengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858754/
https://www.ncbi.nlm.nih.gov/pubmed/31730021
http://dx.doi.org/10.1186/s13287-019-1427-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858754/
https://www.ncbi.nlm.nih.gov/pubmed/31730021
http://dx.doi.org/10.1186/s13287-019-1427-2

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