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Ciglitazone—a human PPARγ agonist—disrupts dorsoventral patterning in zebrafish

Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose homeostasis and adipocyte differentiation. While the role of PPARγ in adipogenesis and diabetes has been extensively studied, little is known about PPARγ function during early...

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Detalles Bibliográficos
Autores principales: Cheng, Vanessa, Dasgupta, Subham, Reddam, Aalekhya, Volz, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858815/
https://www.ncbi.nlm.nih.gov/pubmed/31741801
http://dx.doi.org/10.7717/peerj.8054