Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation

Modification of specific Ser and Thr residues of nucleocytoplasmic proteins with O-GlcNAc, catalyzed by O-GlcNAc transferase (OGT), is an abundant post-translational event essential for proper animal development and dysregulated in various diseases. Due to the rapid concurrent removal by the single...

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Detalles Bibliográficos
Autores principales: Gorelik, Andrii, Galan Bartual, Sergio, Borodkin, Vladimir S., Varghese, Joby, Ferenbach, Andrew T., van Aalten, Daan M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858883/
https://www.ncbi.nlm.nih.gov/pubmed/31695185
http://dx.doi.org/10.1038/s41594-019-0325-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858883/
https://www.ncbi.nlm.nih.gov/pubmed/31695185
http://dx.doi.org/10.1038/s41594-019-0325-8

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