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Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation
Modification of specific Ser and Thr residues of nucleocytoplasmic proteins with O-GlcNAc, catalyzed by O-GlcNAc transferase (OGT), is an abundant post-translational event essential for proper animal development and dysregulated in various diseases. Due to the rapid concurrent removal by the single...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858883/ https://www.ncbi.nlm.nih.gov/pubmed/31695185 http://dx.doi.org/10.1038/s41594-019-0325-8 |