Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

Quantitative mass spectrometry reveals how CD4(+) and CD8(+) T cells re-structure proteomes in response to antigen and mammalian target of rapamycin complex 1 (mTORC1). Analysis of copy numbers per cell of >9000 proteins provides new understanding of T cell phenotypes, exposing the metabolic and...

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Detalles Bibliográficos
Autores principales: Howden, Andrew JM, Hukelmann, Jens L, Brenes, Alejandro, Spinelli, Laura, Sinclair, Linda V, Lamond, Angus I, Cantrell, Doreen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859072/
https://www.ncbi.nlm.nih.gov/pubmed/31591570
http://dx.doi.org/10.1038/s41590-019-0495-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859072/
https://www.ncbi.nlm.nih.gov/pubmed/31591570
http://dx.doi.org/10.1038/s41590-019-0495-x

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