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Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation
Quantitative mass spectrometry reveals how CD4(+) and CD8(+) T cells re-structure proteomes in response to antigen and mammalian target of rapamycin complex 1 (mTORC1). Analysis of copy numbers per cell of >9000 proteins provides new understanding of T cell phenotypes, exposing the metabolic and...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859072/ https://www.ncbi.nlm.nih.gov/pubmed/31591570 http://dx.doi.org/10.1038/s41590-019-0495-x |