Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome

In eukaryotes, accurate chromosome segregation in mitosis and meiosis maintains genome stability and prevents aneuploidy. Kinetochores are large protein complexes, that by assembling onto specialized Cenp-A nucleosomes (1,2), function to connect centromeric chromatin to microtubules of the mitotic s...

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Detalles Bibliográficos
Autores principales: Yan, Kaige, Yang, Jing, Zhang, Ziguo, McLaughlin, Stephen H., Chang, Leifu, Fasci, Domenico, Ehrenhofer-Murray, Ann E., Heck, Albert J.R., Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859074/
https://www.ncbi.nlm.nih.gov/pubmed/31578520
http://dx.doi.org/10.1038/s41586-019-1609-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859074/
https://www.ncbi.nlm.nih.gov/pubmed/31578520
http://dx.doi.org/10.1038/s41586-019-1609-1

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