Population Pharmacokinetic Modeling Of On-Demand And Surgical Use Of Nonacog Beta Pegol (N9-GP) And rFIXFc Based Upon The paradigm 7 Comparative Pharmacokinetic Study

AIM/OBJECTIVE: Understanding pharmacokinetic (PK) differences between standard and extended half-life (EHL) products is important, particularly for factor IX (FIX), where differences are more significant than for factor VIII. Two single-dose PK trials showed N9-GP achieves higher FIX levels and grea...

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Detalles Bibliográficos
Autores principales: Simpson, Mindy L, Kulkarni, Roshni, Escuriola Ettingshausen, Carmen, Medom Meldgaard, Rikke, Cooper, David L, Klamroth, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859083/
https://www.ncbi.nlm.nih.gov/pubmed/32009825
http://dx.doi.org/10.2147/JBM.S217539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859083/
https://www.ncbi.nlm.nih.gov/pubmed/32009825
http://dx.doi.org/10.2147/JBM.S217539

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