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Site-selective (1)H/(2)H labeling enables artifact-free (1)H CPMG relaxation dispersion experiments in aromatic side chains
Aromatic side chains are often key residues in enzyme active sites and protein binding sites, making them attractive probes of protein dynamics on the millisecond timescale. Such dynamic processes can be studied by aromatic (13)C or (1)H CPMG relaxation dispersion experiments. Aromatic (1)H CPMG rel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859156/ https://www.ncbi.nlm.nih.gov/pubmed/31506857 http://dx.doi.org/10.1007/s10858-019-00275-z |