Immunoresponse to Gene-Modified Hematopoietic Stem Cells

Gene transfer to and correction of hematopoietic stem cells (HSCs) are ideal strategies to cure a number of congenital and acquired disorders. However, transgene products may trigger immunological rejection of modified cells, limiting their therapeutic benefits. Preclinical and clinical data indicat...

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Detalles Bibliográficos
Autores principales: Drysdale, Claire M., Tisdale, John F., Uchida, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859277/
https://www.ncbi.nlm.nih.gov/pubmed/31763350
http://dx.doi.org/10.1016/j.omtm.2019.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859277/
https://www.ncbi.nlm.nih.gov/pubmed/31763350
http://dx.doi.org/10.1016/j.omtm.2019.10.010

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