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TMEM16A chloride channel does not drive mucus production
Airway mucus obstruction is the main cause of morbidity in cystic fibrosis, a disease caused by mutations in the CFTR Cl(−) channel. Activation of non-CFTR Cl(−) channels such as TMEM16A can likely compensate for defective CFTR. However, TMEM16A was recently described as a key driver in mucus produc...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Life Science Alliance LLC
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859295/ https://www.ncbi.nlm.nih.gov/pubmed/31732694 http://dx.doi.org/10.26508/lsa.201900462 |