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Nucleic acid cleavage with a hyperthermophilic Cas9 from an uncultured Ignavibacterium
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated 9 (Cas9) systems have been effectively harnessed to engineer the genomes of organisms from across the tree of life. Nearly all currently characterized Cas9 proteins are derived from mesophilic bacteria, and canonical Cas9...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859307/ https://www.ncbi.nlm.nih.gov/pubmed/31659048 http://dx.doi.org/10.1073/pnas.1904273116 |